歐盟評估一種6-植酸酶作為家禽、育肥豬、斷奶仔豬和母豬飼料添加劑的安全性和有效性

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據了解，這種6-植酸酶由米曲霉DSM 33699產生。經過評估，專家小組認為在建議的使用條件下該添加劑對目標物種和環境是安全的。在500 FYT/千克全價飼料下，該添加劑可能對家禽、育肥豬、斷奶仔豬和母豬有效。部分原文報道如下：

The additive RONOZYME?Hiphos (GT/L) contains 6-phytase produced with a genetically modified strain of the filamentous fungus Aspergillus oryzae, it is currently authorised for poultry, pigs for fattening, weaned piglets and sows. The applicant has requested to change the production strain, substituting strain A. oryzae DSM 22594 for A. oryzae DSM 33699. RONOZYME?Hiphos (GT/L), manufactured with the production strain A. oryzae DSM 33699, did not give rise to safety concerns with regard to the genetic modification of the production strain. No viable cells of the production strain nor its recombinant DNA were detected in an intermediate product representative of both final forms of the additive. RONOZYME?Hiphos (GT/L) was considered safe for poultry, pigs for fattening, weaned piglets and sows at the recommended inclusion levels of 500–4,000 FYT/kg complete feed. The use of RONOZYME?Hiphos GT and L manufactured with the production strain A. oryzae DSM 33699 raised no concerns for consumers. In the absence of data on the final formulations, the Panel could not conclude on the potential of the additive to be irritant to eyes or skin, or a skin sensitiser. Due to the proteinaceous nature of the active substance, the additive was considered a respiratory sensitiser. The additive manufactured by A. oryzae DSM 33699 raises no safety concerns for the environment. The additive has the potential to be efficacious in poultry, pigs for fattening, weaned piglets and sows at 500 FYT/kg complete feed.